The creators of The Simpsons television show created the new plot and dialogue; the cast of The Simpsons provided all the character voices. Its characters, including playable versions of Homer, Marge, Bart, Maggie, and Lisa, are all exact replicas of those in the original. Like Grand Theft Auto III from 2001, Hit & Run has an open world, but it does so in a more parodic, Simpsons-esque manner.

On September 16, 2003, The Simpsons: Hit & Run was made available. An action-adventure computer game called The Simpsons: Hit & Run is based on the American animated series of the same name. Each of the seven levels in Hit & Run contains a mission and a supporting plot. In each level, the user can control a single character. Simpsons Hit & Run is a mission-based adventure game with a similar structure to Grand Theft Auto. If you would like to see The Simpsons: Hit and Run on PS4 just tweet @davethach with the hashtag #PS2onPS4 and ask for The Simpsons: Hit and Run. Even if you don't paritculary like the game, it would be nice for PS4 players to be able to play it and it would be nice for us to get a Simpsons game on the PS4. A thread I made a few days ago suggests that a lot of people here would like to see a Simpsons game on PS4, and this is probably the closest we will get.McGinn says the studio developing the title had to "move on" shortly after the licence was awarded to EA. The graphics are average and cel-shaded. The sound effects are funny, and the characters speak in English. There are some hiccups in the voiceovers, but the overall sound is good. The game is recommended for fans of the show. However, it’s hard to recommend this game without spending a large amount of money. The game does have some positives, though. Can I play Simpsons Hit and Run on PS4?

Unfortunately, there isn't a full or detailed guide on how to play Simpsons Hit and Run on PS4 or the remade version of it on PS4.

You may enter the beloved Hit and Run universe once more thanks to Dreams user ReivaJKH's accurate replica of the original. Like many of the fantastic Dreams remakes, including this one of Ghost of Tsushima, this one looks, sounds, and plays a lot like the original. Even though it's not clear if or when The Simpsons: Hit & Run original game will be remade or remastered, Media Molecule's Dreams lets you relive the crazy adventures from the game with its version. Each of its characters is identical to those in the original, with Homer, Marge, Bart, Maggie, and Lisa in playable form. Hit & Run features an open world similar to that of 2001’s Grand Theft Auto III, but done so in more of a satirical way, in typical Simpsons fashion. Though the recreation still needs some work with its open-world aspects (like more variety in buildings and other features to make the world feel more alive), the foundation of an impressive game is there. It’s unclear if its creator plans to keep fleshing things out, but nonetheless, this looks and is presented just like the game you remember. The prospect of seeing The Simpsons: Hit & Run again isn't out of the question given the prevalence of remakes and remasters in the video game industry. Unlike some video games, Hit and Run can be played on PS4. This is because the game features an eclectic cast and you get to explore the town of Springfield. According to Senior Designer Joe McGinn in an interview with GAME, a sequel was in the works. The sequel would have included a more advanced physics engine. However, due to the fact that EA had the rights to make the game, the sequel never materialized.