There have also been side effects. One is that I have slightly less self-control than usual. For example, it's harder to resist buying a chocolate bar or something that I like but isn't good for me. I also seem to get some OCD-like thoughts and phrases that I repeat in my head sometimes. Now you can definitely get a benefit from taking a smaller dose like one capsule a day. That’s still like drinking one and a half ounces of fresh broccoli sprout juice a day, which certainly will be helpful. So while two [capsules] a day provides a more therapeutic dose, if money’s tight or you can only tolerate one capsule a day, let’s say you’re sensitive to sulfur compounds, it’s totally still worth it. Most people will notice the effects within two days to two weeks. Interestingly, the first effect that many people notice is vivid dreams, and I suspect that’s due to the upregulation of BDNF, which improves brain function. The other main effect that people tend to notice right away is some reduction of chronic inflammation or pain. And that will also tend to improve over time as Nrf2 becomes more active. BrocElite can be stored in a cool, dry place. It doesn’t need to be refrigerated if you take it regularly. But if you are storing it for longer periods, you should put it in the fridge. Sulforaphane is a natural plant compound that’s generally well-tolerated. In rare cases, concentrated sulforaphane may cause mild side effects like gas, cramps, constipation, or diarrhea.

Each tablet contains ingredients for added antioxidant benefits. This includes 100 mg of DIM, 50 mg of watercress extract, 50 mg of rosemary extract, and 25 mg of cabbage extract.Specifically, ingested sulforaphane activates what’s called the NRF2 pathway, which increases expression of a battery of cell protective genes, that regulate things like: The reason for not making a hot tea, is that the myrocinase enzyme in moringa is sensitive to heat, and its important to preserve it.

Klomparens EA, Ding Y. The neuroprotective mechanisms and effects of sulforaphane. Brain Circ. 2019;5(2):74-83. doi:10.4103/bc.bc_7_19 Lozanovski VJ, Polychronidis G, Gross W, et al. Broccoli sprout supplementation in patients with advanced pancreatic cancer is difficult despite positive effects-results from the POUDER pilot study. Invest New Drugs. 2020;38(3):776-784. doi:10.1007/s10637-019-00826-zAs mentioned, sulforaphane comes from a range of cruciferous vegetables and sprouts. Unfortunately, overcooking your veggies destroys these compounds. Eating them raw or lightly steaming them is the best choice. Although, I don’t know anyone who enjoys raw broccoli. Plus, you’d have to munch on mountains of the stuff to get the same concentration used in clinical studies.

In terms of consuming them, you’ll probably want to emulate Rhonda, who adds the sprouts to smoothies and blends them in her Blendtec– to mask the taste with other flavors. You want to avoid juicing, as this will discard the pre-biotic fiber that is beneficial to our gut microbiome. Most of your nutrients should come directly from whole foods whenever possible. But that’s not always easy. So are there any contraindications with sulforaphane and BrocElite? Not that I’m aware of at this point. I do have a few patients that are sensitive to sulfur-based compounds in general, like glutathione or [methylsulfonylmethane], and folks with that issue may want to start with maybe one capsule or half [a] capsule and see how they do and then build up to the full dose. But that’s pretty rare. Otherwise, in more than 2,000 studies, sulforaphane has been safe and well-tolerated at the typical doses found in broccoli sprouts and supplements. I suggest a dose of two capsules per day taken at breakfast. And [there are two] reasons [why] I say breakfast. One, it’s generally better to take it with food. In about 10 to 20 percent of people, it will cause mild gastrointestinal discomfort if they take it on an empty stomach. And that’s been more true in my patients with [small intestinal bacterial overgrowth] or other [gastrointestinal] issues. The second reason I suggest taking it [at] breakfast is that because of how it upregulates BDNF levels, it can really increase mental clarity and focus and have all these amazing benefits. But I’ve found in some of my patients, if you take it right before bed, it can actually interfere with getting to sleep because there’s so much activity; there’s so much going on in the brain. So that can easily be avoided by taking it at breakfast, instead of at dinner, instead of before bed. Protected by 2 patents, it is marketed by Ingood by Olga, business unit of Olga group since 2015 which markets the active ingredient Sulfodyne® 5% of active and stabilised sulforaphane. Research suggests sulforaphane may support cardiovascular health thanks to its antioxidant and anti-inflammatory properties.This studyon diabetic patients found that 100 grams of sulforaphane-rich broccoli sprouts daily reduced markers of oxidative stress and LDL cholesterol and increased HDL cholesterol levels.