Hall, Wayne; Weier, Megan (2017). "Lee Robins' studies of heroin use among US Vietnam veterans". Addiction. 112 (1): 177. doi: 10.1111/add.13584. PMID 27650054. S2CID 206974500 . Retrieved July 26, 2022.

Julius Berendes (1902). "De Materia Medica" (in German). Archived from the original on February 8, 2007 . Retrieved May 10, 2007. Jennifer Hull (June 24, 2001). "Eastern Europe Shooting Up Under A Red Star". Time . Retrieved April 17, 2020. Opium poppies are popular and attractive garden plants, whose flowers vary greatly in color, size and form. A modest amount of domestic cultivation in private gardens is not usually subject to legal controls. In part, this tolerance reflects variation in addictive potency. A cultivar for opium production, Papaver somniferum L. elite, contains 91.2 percent morphine, codeine, and thebaine in its latex alkaloids, whereas in the latex of the condiment cultivar "Marianne", these three alkaloids total only 14.0 percent. The remaining alkaloids in the latter cultivar are primarily narcotoline and noscapine. [115] In 1909, the International Opium Commission was founded, and by 1914, 34 nations had agreed that the production and importation of opium should be diminished. In 1924, 62 nations participated in a meeting of the commission. Subsequently, this role passed to the League of Nations, and all signatory nations agreed to prohibit the import, sale, distribution, export, and use of all narcotic drugs, except for medical and scientific purposes. This role was later taken up by the International Narcotics Control Board of the United Nations under Article 23 of the Single Convention on Narcotic Drugs, and subsequently under the Convention on Psychotropic Substances. Opium-producing nations are required to designate a government agency to take physical possession of licit opium crops as soon as possible after harvest and conduct all wholesaling and exporting through that agency. [1] Indochina tax [ edit ] Two men smoked opium in Tonkin in 1923 Globally, opium has gradually been superseded by a variety of purified, semi-synthetic, and synthetic opioids with progressively stronger effects, and by other general anesthetics. This process began in 1804, when Friedrich Wilhelm Adam Sertürner first isolated morphine from the opium poppy. [100] [101] Modern vial of morphine first isolated from opium by Friedrich Sertürner

Heroin abuse

Max Chamka; Translated by Geraldine Ring. "3 grams of opium for 1 dollar". Caucaz europenews . Retrieved May 6, 2007. Opium prohibition in China began in 1729, yet was followed by nearly two centuries of increasing opium use. A massive destruction of opium by an emissary of the Chinese Daoguang Emperor in an attempt to stop opium smuggling by the British led to the First Opium War (1839–1842), in which Britain defeated China. After 1860, opium use continued to increase with widespread domestic production in China. By 1905, an estimated 25 percent of the male population were regular consumers of the drug. Recreational use of opium elsewhere in the world remained rare into late in the 19th century, as indicated by ambivalent reports of opium usage. [44] In 1906, 41,000 tons were produced, but because 39,000 tons of that year's opium were consumed in China, overall usage in the rest of the world was much lower. [48] These figures from 1906 have been criticized as overestimates. [49] A Chinese opium house; photographed in 1902 Martin, Steven. The Art of Opium Antiques. Chiang Mai: Silkworm Books, 2007. Photographs and history of Chinese and Vietnamese opium-smoking paraphernalia. The earliest clear description of the use of opium as a recreational drug in China came from Xu Boling, who wrote in 1483 that opium was "mainly used to aid masculinity, strengthen sperm and regain vigor", and that it "enhances the art of alchemists, sex and court ladies". He also described an expedition sent by the Ming dynasty Chenghua Emperor in 1483 to procure opium for a price "equal to that of gold" in Hainan, Fujian, Zhejiang, Sichuan and Shaanxi, where it is close to the western lands of Xiyu. A century later, Li Shizhen listed standard medical uses of opium in his renowned Compendium of Materia Medica (1578), but also wrote that "lay people use it for the art of sex," in particular the ability to "arrest seminal emission". This association of opium with sex continued in China until the end of the 19th century.

a b c M J Brownstein (June 15, 1993). "A brief history of opiates, opioid peptides, and opioid receptors". Proceedings of the National Academy of Sciences of the United States of America. 90 (12): 5391–5393. Bibcode: 1993PNAS...90.5391B. doi: 10.1073/pnas.90.12.5391. PMC 46725. PMID 8390660. During the Communist era in Eastern Europe, poppy stalks sold in bundles by farmers were processed by users with household chemicals to make kompot (" Polish heroin"), and poppy seeds were used to produce koknar, an opiate. [99] Obsolescence [ edit ] Apothecary vessel for storage of opium as a pharmaceutical, Germany, 18th or 19th centurya b c d e Alfred W. McCoy. "Opium History, 1858 to 1940". Archived from the original on April 4, 2007 . Retrieved May 4, 2007.

William Travis Hanes; Frank Sanello (2004). Opium Wars: The Addiction of One Empire and the Corruption of Another. Sourcebooks, Inc. pp.78–. ISBN 978-1-4022-0149-3.

What is Opium?

Dioscorides,Introduction to The Herbal of Dioscorides the Greek Poppy crop from the Malwa in India (probably Papaver somniferum var. album [1]) This section needs to be updated. Please help update this article to reflect recent events or newly available information. ( October 2022) Marc Andre Matten, ed. (December 9, 2011). Places of Memory in Modern China: History, Politics, and Identity. BRILL. p.271. ISBN 978-90-04-21901-4. Smoking, snorting or orally ingesting heroin does not produce an intense "rush" as might be experienced with intravenous (IV) injection. In June 2007, the council launched a "Poppy for Medicines" project that provides a technical blueprint for the implementation of an integrated control system within Afghan village-based poppy for medicine projects: the idea promotes the economic diversification by redirecting proceeds from the legal cultivation of poppy and production of poppy-based medicines. [143] There has been criticism of the Senlis report findings by Macfarlan Smith, who argue that though they produce morphine in Europe, they were never asked to contribute to the report. [144] Cultivation in the UK [ edit ]