Pure L CARNITINE 3000 mg Liquid Shots | High Strength, Weight Loss, Fat Burner, High Concentration | Tangerine Flavor | Energy Booster | 20 Easy Opening Vials. UK Vegan. N2 Natural Nutrition

£0.36
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Pure L CARNITINE 3000 mg Liquid Shots | High Strength, Weight Loss, Fat Burner, High Concentration | Tangerine Flavor | Energy Booster | 20 Easy Opening Vials. UK Vegan. N2 Natural Nutrition

Pure L CARNITINE 3000 mg Liquid Shots | High Strength, Weight Loss, Fat Burner, High Concentration | Tangerine Flavor | Energy Booster | 20 Easy Opening Vials. UK Vegan. N2 Natural Nutrition

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Price: £0.36
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Jogl G, Tong L: Crystal structure of carnitine acetyltransferase and implications for the catalytic mechanism and fatty acid transport. Cell. 2003 Jan 10;112(1):113-22. [ Article] The plasma concentration profiles of levocarnitine after a slow 3 minute intravenous bolus dose of 20 mg/kg of CARNITOR ® were described by a two-compartment model. Following a single i.v. administration, approximately 76% of the levocarnitine dose was excreted in the urine during the 0-24h interval. Using plasma concentrations uncorrected for endogenous levocarnitine, the mean distribution half life was 0.585 hours and the mean apparent terminal elimination half life was 17.4 hours. Bid farewell to juggling multiple food supplements. Get your daily dose of L-Carnitine with our Vials, boosting your energy and overall health becomes straightforward and efficient. Crafted with precise dosages for hassle free use, each vial paves the way to the vitality you've been seeking Mutagenicity tests performed in Salmonella typhimurium, Saccharomyces cerevisiae, and Schizosaccharomyces pombe indicate that levocarnitine is not mutagenic. No long-term animal studies have been performed to evaluate the carcinogenic potential of levocarnitine. Pregnancy L-carnitine is known to interact with thyroid medication, reducing its efficacy. It increases the efficacy of Warfarin and Acenocoumarol, thereby raising the risk of excessive bleeding or bruising.

L-Carnitine has also been associated with many other conditions for which there is negligible or conflicting data. These include acne, autism, arrhythmia, androgenic alopecia, tiredness and neuropathy from chemotherapy, and many more. The research data on these therapies are insufficient to lend any credence to the claims. Dosage The word carnitine is derived from the Latin word carnus, meaning meat. The redder the meat, the higher the carnitine content. After one week of CARNITOR ® therapy (3 doses), all patients had trough concentrations between 54 and 180 μmol/L (normal 40-50 μmol/L) and concentrations remained relatively stable or increased over the course of the study.Levocarnitine may decrease the excretion rate of Abacavir which could result in a higher serum level. Brooks, H., Goldberg, L., Holland, R. et al. 1977. Carnitine-induced effects on cardiac and peripheral hemodynamics. J. Clin. Pharmacol. 17:561-568. The plasma concentration profiles of levocarnitine after a slow 3 minute intravenous bolus dose of 20 mg/kg of levocarnitine were described by a two-compartment model. Following a single intravenous administration, approximately 76% of the levocarnitine dose was excreted in the urine during the 0 to 24 hour interval. Using plasma concentrations uncorrected for endogenous levocarnitine, the mean distribution half life was 0.585 hours and the mean apparent terminal elimination half life was 17.4 hours. Waldner R, Laschan C, Lohninger A, Gessner M, Tuchler H, Huemer M, Spiegel W, Karlic H: Effects of doxorubicin-containing chemotherapy and a combination with L-carnitine on oxidative metabolism in patients with non-Hodgkin lymphoma. J Cancer Res Clin Oncol. 2006 Feb;132(2):121-8. Epub 2005 Nov 8. [ Article]

The dosage required depends upon the specific inborn error of metabolism concerned and the severity of presentation at the time of treatment. However, the following can be considered as a general guide. Although research to date suggests that L-carnitine is indicated for these conditions, there isn’t much conclusive evidence to support the claims. Elimrani I, Lahjouji K, Seidman E, Roy MJ, Mitchell GA, Qureshi I: Expression and localization of organic cation/carnitine transporter OCTN2 in Caco-2 cells. Am J Physiol Gastrointest Liver Physiol. 2003 May;284(5):G863-71. Epub 2003 Jan 10. [ Article]

Levocarnitine may decrease the excretion rate of Aclidinium which could result in a higher serum level.

The absolute bioavailability of levocarnitine from the two oral formulations of levocarnitine, calculated after correction for circulating endogenous plasma concentrations of levocarnitine, was 15.1 ± 5.3% for Levocarnitine Tablets and 15.9 ± 4.9% for Levocarnitine Oral Solution.For the prevention and treatment of carnitine deficiency in patients with end stage renal disease who are undergoing dialysis. DOSAGE AND ADMINISTRATION It is recommended that a plasma carnitine concentration be obtained prior to beginning this parenteral therapy. Weekly and monthly monitoring is recommended as well. This monitoring should include blood chemistries, vital signs, plasma carnitine concentrations (the plasma free carnitine concentration should be between 35 and 60 µmol/L) and overall clinical condition.

Whether you are an athlete, a bodybuilder or just strive to look better you must have faced the challenge of losing weight. Zumub’s L-Carnitine 4000 vials can simplify this process. In a pharmacokinetic study where five normal adult male volunteers received an oral dose of [ 3H-methyl]-L-carnitine following 15 days of a high carnitine diet and additional carnitine supplement, 58 to 65% of the administered radioactive dose was recovered in the urine and feces in 5 to 11 days. Maximum concentration of [ 3H-methyl]-L-carnitine in serum occurred from 2 to 4.5 hr after drug administration. Major metabolites found were trimethylamine N-oxide, primarily in urine (8% to 49% of the administered dose) and [ 3H]-y-butyrobetaine, primarily in feces (0.44% to 45% of the administered dose). Urinary excretion of levocarnitine was about 4 to 8% of the dose. Fecal excretion of total carnitine was less than 1% of the administered dose. 10 Notice: Trying to get property 'language' of non-object in eval() (line 2 of /home/vivatuneuk/domains/vivatuneuk.co.uk/public_html/modules/php/php.module(80) : eval()'d code). Christiansen, R., Bremer, J. 1976. Active transport of butyrobetaine and carniitine into isolated liver cells. Biochim. Biophys. Acta 448:562-577. The recommended dose is 50 mg/kg given as a slow 2 to 3 minute bolus injection or by infusion. Often a loading dose is given in patients with severe metabolic crisis, followed by an equivalent dose over the following 24 hours. It should be administered every 3 hours or every 4 hours, and never less than every 6 hours either by infusion or by intravenous injection. All subsequent daily doses are recommended to be in the range of 50 mg/kg or as therapy may require. The highest dose administered has been 300 mg/kg.Total body clearance of levocarnitine (Dose/AUC including endogenous baseline concentrations) was a mean of 4.00 L/h. Acemetacin may decrease the excretion rate of Levocarnitine which could result in a higher serum level.



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