Actinic keratosis is usually easy to diagnose clinically or by dermoscopy(see actinic keratosis dermoscopy). Occasionally, a biopsy is necessary, for example, to exclude SCC, or if treatment fails. What is the treatment for actinic keratoses? Bis-ethylhexyloxyphenol metoxifenil triazin, etilhexil triazona, izoamil p-metoxicinamat, etilhexil metoxicinamat, metilen bis-benzotriazolil tetrametil-butilfenol, butil metoxibenzoilmetan, propilparaben, metilparaben, excipienti. Crioterapia: vindecarea dureaza 5-10 zile la nivelul fetei, 3-4 saptamani la nivelul mainilor si 6 saptamani sau chiar mai mult la nivelul picioarelor The skin surface varies from one individual to another; the table below gives the approximate number of doses (= pressures) required. Where and how to use Actinica® Lotion? Limiteaza timpul de expunere la soare, in special intre orele 10.00-14.00. Nu te expune excesiv la soare, astfel incat sa te bronzezi sau sa te arzi. Expunerea la soare care se acumuleaza in timp, de asemenea, cauzeaza keratoza solara

If you plan to use cosmetics, wait until the lotion has penetrated the skin before applying the other products. Din nefericire exista un mic risc de reaparitie al keratozelor actinice, chiar si dupa un tratament efectuat corect. In aceste cazuri, dupa cum spuneam, tratamentul poate fi repetat fara probleme sau se poate incerca un alt tratament.

Prevention of actinic keratoses

alte semne de foto-imbatranire (riduri, ingrosarea pielii, schimbarea texturii pielii – aspect tern, pori dilatati, piele inelastica, numeroase lentigo solare, etc) Photodynamic therapy (PDT) involves applying a photosensitiser (a porphyrin chemical such as methyl aminolevulinic acid) to the affected area prior to exposing it to a source of visible light. Aparitia acestor leziuni cutanate premaligne poate fi prevenita prin utilizarea cu rigurozitate a cremelor de fotoprotectie. Chiar si keratozele actinice deja prezente se pot ameliora prin folosirea de creme de fotoprotectie cu factor (SPF) 50+ pe zonele afectate, pe tot parcursul anului. National Cancer Intelligence Network. Non-melanoma skin cancer in England, Scotland, Northern Ireland, and Ireland. http://www.ncin.org.uk/view?rid=2178 Last accessed February 2014

Crioterapia. Este tratamentul standard pentru keratoza actinica si consta in inghetarea zonei cu azot lichid. Pot sa apara inflamatia si tumefierea zonei tratate si, ocazional, vezicule. Se formeaza o mica crusta si pe masura ce aceasta se vindeca apare piele noua, sanatoasa In plus, vreau sa va spun despre “cancerizarea in camp”. Desi nu este nimic nou, faptul ca un cancer de piele poate sa apara brusc pe piele anterior normala e greu de acceptat de majoritatea pacientilor. The number and severity of actinic keratoses can also be reduced by taking nicotinamide (vitamin B3) 500 mg twice daily. What is the outlook for actinic keratoses? Daca se trateaza la timp, toate leziunile de keratoza actinica pot fi indepartate inainte de a se transforma in cancer de piele. Daca sunt lasate netratate, unele din acestea pot progresa catre carcinom cu celule scuamoase - un tip de cancer de piele care nu este amenintator de viata daca este diagnosticat si tratat precoce.for better protection, apply it to areas of the skin that will be most exposed to ultraviolet radiation and which are not covered with clothing; If you have more than 1 patch, or a patch is causing you problems such as pain and itchiness, treatment is usually recommended. Uneori in faza pre-terapeutica este necesara utilizarea de agenti keratolitici (uree, acid salicilic, retinoizi topici). Acestia sunt utili pentru “subtierea” prealabila a leziunilor astfel permitand o penetrabilitate mai buna a cremelor-medicament.

Fluorouracil is a cytotoxic agent. The cream formulation is applied once or twice daily for 2 to 8 weeks.Its effect may be enhanced by calcipotriolointment.5-fluorouracil may be available as a combination product along with salicylic acid. Keratozele actinice plane, asimptomatice pot fi lasate netratate daca aceasta este dorinta expresa a pacientului, insa trebuie tinute sub observatie prin monitorizare video-dermatoscopica.Although Actinica® Lotion provides very high protection for several hours, skin that is very sensitive and / or previously damaged by UV radiation should never be overexposed to sunlight. Properly applied, Actinica® Lotion helps prevent skin cancer caused by UV rays. The lotion should not be used to increase the time you spend outside.

Apply once daily with just a sufficient amount, as measured and dispensed in proper dosage by the product’s container. Diclofenaculeste mai des utilizat ca medicament antiinflamator. Aplicat sub forma de gel de doua ori pe zi timp de 3 luni, este destul de bine tolerat in tratamentul keratozelor actinicei. 5-Fluorouraciluleste un agent citotoxic. Unguentul se aplica o data sau de doua ori pe zi, timp de 2 – 8 saptamani. Crema cu 5 fluorouracil este uneori combinata cu acidul salicilic. Efectul sau poate fi intensificat prin unguent cu calcipotriol. Imiquimodcrema este un modificator de raspuns imun. Se aplica de 2 -3 ori pe saptamana timp de 4 – 16 saptamani. Keratoza actinica si riscul de cancer metode conservative: tratament medical, cu produse farmaceutice cu aplicare topica – creme, geluri, etc Actinica Lotion este un dispozitiv medical cu spectru larg de protectie UV. Special dezvoltat pentru persoanele care au un risc mai mare de a dezvolta cancer de piele din cauza expunerii UV. Cunningham TJ, Tabacchi M, Eliane JP, Tuchayi SM, Manivasagam S, Mirzaalian H,Turkoz A, Kopan R, Schaffer A, Saavedra AP, Wallendorf M, Cornelius LA, DemehriS. Randomized trial of calcipotriol combined with 5-fluorouracil for skin cancer precursor immunotherapy. J Clin Invest. 2017 Jan 3;127(1):106–16. doi:10.1172/JCI89820. PubMed PMID: 27869649; PubMed Central PMCID: PMC5199703. PubMed

Actinica Lotion especially works well for people who are at a higher risk of contracting skin cancer, including: Keratoza actinica poate avea aspect variabil. La inceput, poate fi greu de observat si e mai usor de simtit, deoarece poate fi aspra. Unele au culoarea pielii, altele sunt roz sau maro rosiatic. Ocazional dezvolta un strat gros, solzos. Pielea inconjuratoare pare adesea parea deteriorata de soare. Partea superioara a fiecareia poate avea o crusta alb-galbena, solzoasa. Roseata se poate dezvolta pe pielea din jur. Cauze ale keratozei actinice (solare) ACTINICA Lotion contains a combination of photostable UV filters, which absorb, reflect and scatter a broad spectrum of UV radiation. It is highly effective in protecting skin from ultraviolet B (UVB) as well as from ultraviolet A (UVA) radiation. Its UVB and UVA protection level meets the highest category, “very high UV protection”, as established by the European Commission recommendation.