If you are pregnant, trying to become pregnant, or breastfeeding, speak to your doctor or our pharmacist before taking this product. If you suffer from any allergies, ask your doctor or our pharmacist if this medicine is right for you. Dosage: Adults, the elderly and children aged 16 years and over: Two capsules every four hours as required. Maximum 8 capsules (4 doses) in any 24 hour period. Do not take continuously for more than 5 days without medical advice. Plasma-protein binding is negligible at usual therapeutic concentrations but increases with increasing concentrations. Side effects: See SPC for full details. Hypersensitivity reactions e.g. rhinitis, angioedema, urticaria, bronchospasm, skin reactions and anaphylaxis. Nausea, vomiting, dyspepsia, gastrointestinal ulceration, gastrointestinal haemorrhage and gastritis. Renal dysfunction, increased blood uric acid levels, elevation in aminotransferase levels, prolonged bleeding time, thrombocytopenia, ecchymosis, sodium and fluid retention bronchospasm, tinnitus, temporary hearing loss, nervousness and dizziness. There have been cases of bronchospasm with paracetamol, but these are more likely in asthmatics sensitive to aspirin or other NSAIDs.

Contains paracetamol. Talk to a doctor at once if you take too much of this medicine, even if you feel well. This is because too much paracetamol can cause delayed, serious liver damage.

Contains paracetamol. Do not take anything else containing paracetamol whilst taking this medicine. Do not take more medicine than the label tells you to. Talk to a doctor at once if you take too much of this medicine, even if you feel well. If you do not get better, talk to your doctor. If you have a stinking cold, you might consider using Beechams all in one to relieve your symptoms. We look at Beechams all in one dosage, possible side-effects and medicine interactions: What is Beechams all in one used for? Sympathomimetic amines, such as phenylephrine, act on alpha-adrenergic receptors of the respiratory tract to produce vasoconstriction, which temporarily reduces the swelling associated with inflammation of the mucous membranes lining the nasal and sinus passages. This allows the free drainage of the sinusoidal fluid from the sinuses.

Paracetamol probably produces antipyresis by acting on the hypothalamic heat- regulating centre to produce peripheral vasodilation resulting in increased blood flow through the skin, sweating and heat loss. The central action probably involves inhibition of prostaglandin synthesis in the hypothalamus.If you're taking medicines for high blood pressure you shouldn't take Beechams max strength all in one, because the decongestant may make your blood pressure medicine less effective. Paracetamol is a painkiller that can relieve a headache and mild to moderate aches and pains associated with colds and flu. Paracetamol also works to bring down a fever and this stops you feeling hot or shivery. doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: Women who are pregnant. (Phenylephrine has blood vessel constricting effects that could restrict blood supply to the placenta, or cause problems for women with a history of pre-eclampsia. Ask your doctor or pharmacist for further advice on how to treat cold and flu symptoms during pregnancy.) Liver damage is possible in adults who have taken 10g or more of paracetamol. Ingestion of 5g or more of paracetamol may lead to liver damage if the patient has risk factors (see below).

Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or Treatment with activated charcoal should be considered if the overdose has been taken within 1 hour. Plasma paracetamol concentration should be measured at 4 hours or later after ingestion (earlier concentrations are unreliable). Treatment with N-acetylcysteine may be used up to 24 hours after ingestion of paracetamol, however, the maximum protective effect is obtained up to 8 hours post-ingestion. The effectiveness of the antidote declines sharply after this time. If required the patient should be given intravenous N-acetylcysteine, in line with the established dosage schedule. If vomiting is not a problem, oral methionine may be a suitable alternative for remote areas, outside hospital. Management of patients who present with serious hepatic dysfunction beyond 24h from ingestion should be discussed with the NPIS or a liver unit. a, Is on long term treatment with carbamazepine, phenobarbitone, phenytoin, primidone, rifampicin, St John's Wort or other drugs that induce liver enzymes. Applies to acetaminophen / guaifenesin / phenylephrine: oral liquid. Serious side effects of Beechams All-in-One Paracetamol is thought to relieve pain by reducing the production of prostaglandins in the brain and spinal cord. It works to bring down a fever by affecting an area of the brain that regulates our body temperature (the hypothalamic heat-regulating center). This stops you feeling hot or shivery.

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The antidiabetic medicines exenatide, lixisenatide and liraglutide may slow down the absorption of paracetamol into the bloodstream, so it might take longer to work if you're using one of these medicines to treat your diabetes. Ask your pharmacist for more advice. Adverse events from historical clinical trial data are both infrequent and from small patient exposure. Side effects: See SPC for full details. Hypersensitivity reactions including anaphylaxis, skin rashes, angioedema and SJS. Bronchospasm, hepatic dysfunction, thrombocytopenia, agranulocytosis, nervousness, irritability, restlessness, excitability, headache, dizziness, insomnia, increased blood pressure, nausea, vomiting, mydriasis, acute angle glaucoma, tachycardia, palpitations, dysuria and urinary retention.