Emetrol Nausea and Upset Stomach Relief Liquid Medication, Cherry - 4 oz Bottle

£9.9
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Emetrol Nausea and Upset Stomach Relief Liquid Medication, Cherry - 4 oz Bottle

Emetrol Nausea and Upset Stomach Relief Liquid Medication, Cherry - 4 oz Bottle

RRP: £99
Price: £9.9
£9.9 FREE Shipping

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Description

Some side effects of phosphorated carbohydrate solution may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Emetrol has been associated with prolongation of the QT interval on the electrocardiogram. During post-marketing surveillance, there have been very rare cases of QT prolongation and torsades de pointes in patients taking Emetrol. These reports included patients with confounding risk factors, electrolyte abnormalities and concomitant treatment which may have been contributing factors. In subjects with moderate hepatic impairment (Pugh score 7 to 9, Child-Pugh rating B), the AUC and C max of Emetrol is 2.9- and 1.5-fold higher, respectively, than in healthy subjects. The unbound fraction is increased by 25%, and the terminal elimination half-life is prolonged from 15 to 23 hours. Subjects with mild hepatic impairment have a somewhat lower systemic exposure than healthy subjects based on C max and AUC, with no change in protein binding or terminal half-life. Subjects with severe hepatic impairment were not studied. Emetrol should not be used in patients with moderate or severe hepatic impairment. It is the brand name of a combination of fructose, dextrose, and phosphoric acid. This medication belongs to a group of medications called antiemetics. This medicine contains fructose and should not be taken by people with hereditary fructose intolerance, an inborn error offructosemetabolism caused by a deficiency of the enzyme aldolase B.

In subjects with severe renal insufficiency (creatinine clearance<30 ml/min/1.73m2) the elimination half-life of Emetrol was increased from 7.4 to 20.8 hours, but plasma drug levels were lower than in healthy volunteers.

Patient Handout

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical Very common (>1/10); common (>1/100 to <1/10); uncommon (>1/1,000 to <1/100); rare (>1/10,000 to <1/1,000); very rare (<1/10,000), where frequency can not be estimated from clinical trials data, it is recorded as “Not known”.

Epidemiological studies showed that Emetrol was associated with an increased risk of serious ventricular arrhythmias or sudden cardiac death. A higher risk was observed in patients older than 60 years, patients taking daily doses greater than 30mg, and patients concurrently taking QT_prolonging drugs or CYP3A4 inhibitors. Along with its needed effects, phosphorated carbohydrate solution (the active ingredient contained in Emetrol) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.It is typically used to prevent vomiting and nausea which may be caused by cancer chemotherapy, surgery, or radiation treatment. Dosage DRUG INTERACTIONS: Consult your pharmacist.Keep a list of all your medications with you, and share the list with your doctor and pharmacist. In accordance with ICH—E14 guidelines, a thorough QT study was performed. This study included a placebo, an active comparator and a positive control and was conducted in healthy subjects with up to 80 mg per day 10 or 20 mg administered 4 times a day of Emetrol. This study found a maximal difference of QTc between Emetrol and placebo in LS-means in the change from baseline of 3.4 msec for 20 mg Emetrol administered 4 times a day on Day 4. The 2-sided 90 % CI (1.0 to 5.9 msec) did not exceed 10 msec. No clinically relevant QTc effects were observed in this study when Emetrol was administered at up to 80 mg/day (i.e., more than twice the maximum recommended dosing). Emetrol is contraindicated in patients with known existing prolongation of cardiac conduction intervals, particularly QTc, in patients with significant electrolyte disturbances (hypokalaemia, hyperkalaemia, hypomagnesaemia), or bradycardia, or in patients with underlying cardiac diseases such as congestive heart failure due to increased risk of ventricular arrhythmia. Electrolyte disturbances (hypokalaemia, hyperkalaemia, hypomagnesaemia) or bradycardia are known to be conditions increasing the proarrythmic risk. to make sure that it is safe for you to take Emetrol (fructose, dextrose, and phosphoric acid) with all of your drugs and health problems. Do not start, stop, or change the dose of

Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using Emetrol (fructose, dextrose, and phosphoric acid) For an individual experiencing episodes of nausea and vomiting, finding immediate relief is a top priority. OTC products for the treatment of nausea and vomiting include antihistamines, bismuth subsalicylate, antacids, histamine 2 (H 2)- receptor antagonists, and phosphorated carbohydrate solution. The usual recommended dose for children is5–10mL at 15 minutes intervals, as required. The usual recommended dose for adults is15–30mL at 15 minutes intervals, as required. It is typically used to relieve nausea by calming the stomach. Nausea is the sensation of an urge to vomit. It can be acute and short-lived, or it can be prolonged. Common causes of nausea include:

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for 2 on selected vitamins, supplements health foods and complementary medicines. Cheapest free. Subject to availability In the presence of inhibition of the metabolism via CYP3A4 free plasma concentrations of Emetrol can rise up to 3-fold.



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