Derikx LA, Dieleman LA Hoentjen F. Probiotics and prebiotics in ulcerative colitis. Best Pract Res Clin Gastroenterol 2016; 30: 55-71. [ PubMed abstract] Munoz P, Bouza E, Cuenca-Estrella M, Eiros JM, Perez MJ, Sanchez-Somolinos M, et al. Saccharomyces cerevisiae fungemia: an emerging infectious disease. Clin Infect Dis 2005;40:1625-34. [ PubMed abstract]

ProVen Probiotics for Women - with Cranberry and Vitamin B6 ProVen Probiotics for Women - with Cranberry and Vitamin B6

Shimizu M, Hashiguchi M, Shiga T, Tamura HO, Mochizuki M. Meta-analysis: effects of probiotic supplementation on lipid profiles in normal to mildly hypercholesterolemic individuals. PLoS One 2015;10:e0139795. [ PubMed abstract] Taking friendly bacteria such as Acidophilus and Bifidus alongside and following antibiotics may help to maintain a balanced microbiota. Multi-strain ultra-high-strength live bacteria

The urogenital tract comprises both the urinary tract and the vagina and both contain a microbiome (bacteria) in the same way as the gastrointestinal tract. Lactobacillus is the primary bacteria of the vagina of healthy women and the growth of too many other strains can lead to an imbalance in the natural bacteria of the vagina. Ford AC, Quigley EM, Lacy BE, Lembo AJ, Saito YA, Schiller LR, et al. Efficacy of prebiotics, probiotics, and synbiotics in irritable bowel syndrome and chronic idiopathic constipation: systematic review and meta-analysis. Am J Gastroenterol 2014;109:1547-61; quiz 6, 62. [ PubMed abstract] Ghouri YA, Richards DM, Rahimi EF, Krill JT, Jelinek KA DuPont AW. Systematic review of randomized controlled trials of probiotics, prebiotics, and synbiotics in inflammatory bowel disease. Clin Exp Gastroenterol 2014; 7: 473-87. [ PubMed abstract] Numerous probiotic studies have evaluated the effects of various species and strains of bacteria on the prevention of atopic dermatitis, and several meta-analyses have synthesized the findings of these studies. These studies and meta-analyses show that exposure to probiotics during pregnancy and in early infancy might reduce the risk of developing atopic dermatitis in children. For example, a 2018 meta-analysis included 27 randomized controlled trials (RCTs) and one controlled cohort study in a total of 6,907 infants and children exposed to probiotics in utero for 2 weeks to 7 months (via maternal oral supplementation) and/or by oral administration to the infants after birth for 2 to 13 months [ 13]. Between age 6 months and 9 years, probiotic treatment with single strains or mixtures that included Lactobacillus, Bifidobacterium, and Propionibacterium strains significantly reduced the risk of atopic dermatitis from 34.7% in the control group to 28.5% in the probiotic group. An assessment of 11 randomized clinical trials with a total of 2,444 participants showed that LGG is most effective in treating infectious diarrhea at a daily dose of at least 10 10 CFU [ 20, 21]. A review of 22 randomized clinical trials with a total of 2,440 participants age 1 month to 15 years found that Saccharomyces boulardii (most commonly 10 9 to 10 10 CFU/day for 5–10 days) reduced both duration of diarrhea and stool frequency [ 22]. In both of these analyses, LGG and Saccharomyces boulardii reduced the duration of acute infectious diarrhea by approximately 1 day. However, two subsequent clinical trials found that a 5-day course of LGG (1x10 10 CFU twice per day taken alone in one trial and a total of 4x10 9 CFU twice per day of LGG and L. helveticus R0052 in the other) was no better than placebo at treating or improving the outcomes of acute gastroenteritis in 1,729 infants and small children presenting to pediatric emergency departments [ 23, 24].

Probiotics for Kids - ProVen Probiotics | Life Concentrated Probiotics for Kids - ProVen Probiotics | Life Concentrated

Cho YA, Kim J. Effect of probiotics on blood lipid concentrations: a meta-analysis of randomized controlled trials. Medicine (Baltimore) 2015;94:e1714. [ PubMed abstract] Trusted Customer | Independent review via Feefo Friendly bacteria alongside and following antibiotics Sairenji T, Collins KL Evans DV. An update on inflammatory bowel disease. Prim Care 2017; 44: 673-92. [ PubMed abstract]

The International Scientific Association for Probiotics and Prebiotics defines probiotics as "live microorganisms that, when administered in adequate amounts, confer a health benefit on the host" [ 1]. These microorganisms, which consist mainly of bacteria but also include yeasts, are naturally present in fermented foods, may be added to other food products, and are available as dietary supplements. However, not all foods and dietary supplements labeled as probiotics on the market have proven health benefits. A meta-analysis of 30 RCTs with 1,624 participants (mostly adults age 18 years or older) demonstrated that those treated with probiotics for 3 to 12 weeks had 7.8 mg/dL lower total cholesterol and 7.3 mg/dL lower LDL cholesterol concentrations than those treated with placebo [ 54]. In subgroup analyses, the benefits of probiotics were slightly greater in studies that lasted 8 weeks or longer and in participants who had baseline cholesterol levels higher than 240 mg/dL. Among the strains included in more than three studies, Lactobacillus acidophilus, a mixture of Lactobacillus acidophilus and Bifidobacterium lactis, and Lactobacillus plantarum were associated with significant reductions in total and LDL cholesterol concentrations, but Lactobacillus helveticus and Enterococcus faecium were not. In a smaller meta-analysis of 11 RCTs in 602 adults with normal or high cholesterol levels, those treated with probiotics for 2 to 10 weeks had 6.6 mg/dL lower total cholesterol and 8.5 mg/dL lower LDL cholesterol levels than those treated with placebo, but the probiotic treatment had no significant effects on HDL cholesterol levels [ 55]. The effects were most pronounced with consumption of probiotics for more than 4 weeks by participants with hypercholesterolemia and those age 45 or older. In both meta-analyses, participants included both healthy adults and adults with hypercholesterolemia, CVD, diabetes, or obesity. Several meta-analyses have assessed the role of probiotics in patients with IBS [ 42-46]. Most have found that probiotics have a positive, although modest, beneficial effect. For example, a meta-analysis of 23 RCTs in a total of 2,575 patients found that, overall, probiotics reduced the risk that IBS symptoms would persist or not improve by 21% [ 42]. Various species and strains of probiotics had beneficial effects on global IBS symptoms, abdominal pain, bloating, and flatulence scores, but the quality of the studies was low. Some combinations of probiotics were superior to individual strains in this analysis, but no specific combination was superior to another. A second meta-analysis of 15 RCTs in a total of 1,793 patients with IBS found that probiotics reduced overall symptoms and abdominal pain more than placebo after 8 to 10 weeks of therapy; in children, these supplements also improved mucosal barrier function [ 43]. Research into the role of the microbiome in health has to date included studies on digestive issues such as irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD), immunity (including allergy, respiratory tract infections and autoimmunity), the gut-brain axis and general areas of health, such as energy and weight.

A Healthy Gut for a Healthy Life Concentrated - Probiotics

Kadooka Y, Sato M, Ogawa A, Miyoshi M, Uenishi H, Ogawa H, et al. Effect of Lactobacillus gasseri SBT2055 in fermented milk on abdominal adiposity in adults in a randomised controlled trial. Br J Nutr 2013;110:1696-703. [ PubMed abstract] Ortiz-Lucas M, Tobias A, Saz P, Sebastian JJ. Effect of probiotic species on irritable bowel syndrome symptoms: A bring up to date meta-analysis. Rev Esp Enferm Dig 2013;105:19-36. [ PubMed abstract]Szajewska H, Guarino A, Hojsak I, Indrio F, Kolacek S, Shamir R, et al. Use of probiotics for management of acute gastroenteritis: a position paper by the ESPGHAN Working Group for Probiotics and Prebiotics. J Pediatr Gastroenterol Nutr 2014;58:531-9. [ PubMed abstract] Sanders ME. Clinical use of probiotics: what physicians need to know. Am Fam Physician 2008;78:1026. [ PubMed abstract] Subgroup analyses showed that the use of probiotics during both the prenatal and postnatal periods significantly reduced the incidence of dermatitis; however, probiotics taken either prenatally only or postnatally only did not. In addition, the effects of probiotic treatment varied by probiotic strain. For example, supplementation with either Lactobacillus rhamnosus or Lactobacillus paracasei significantly reduced the incidence of atopic dermatitis, whereas supplementation with Lactobacillus reuteri or Lactobacillus acidophilus did not.