Evaluations of the Joint FAO/WHO Joint Committee on Food Additives (JEFCO): Gentian violet. (2013). One 2020 research review and one 2017 study found gentian violet as effective as the drug nystatin in treating HIV thrush infections. Irritation. High concentrations of gentian violet have been associated with skin irritation, especially of the lining of the eyes, gastrointestinal tract, and genital tract. Always use low-concentration doses. Other research suggests that perhaps gentian violet has a higher success rate for treatment than nystatin, for example.

SAFETY DATA SHEET - Fisher Sci SAFETY DATA SHEET - Fisher Sci

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. Whaley SG, et al. (2017). Azole antifungal resistance in Candida albicansand emerging non- albicans Candidaspecies. Next day delivery is unavailable to more rural regions & areas. Other delivery timescales to these areas may also be affected. Gentian violet has been used as a topical option to treat thrush for centuries, but the studies are still inconclusive.Some suggest that it may have antifungal and antibacterial qualities and be an affordable, effective agent for conditions including thrush.

Gentiana verna | spring gentian Alpine Rockery/RHS Gardening Gentiana verna | spring gentian Alpine Rockery/RHS Gardening

Europe. The United Kingdom (UK) and France have also limited the use of gentian violet. The UK allows its use only on unwounded skin. France has banned the use of gentian violet cosmetic products. Laboratory studies have shown that gentian violet is capable of causing cancer in mice, but there is little evidence of this occurring in humans Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. As mentioned above, gentian violet has been identified as a potential carcinogen, mutagen (substance causing DNA mutations), and toxin. Also, reports have been made about side effects in babies, including: Gentian Violet causes significant staining, so you will need to use caution with any surfaces or clothing.Oral thrush, or oral candidiasis, is a yeast infection of the mouth. Oral thrush is usually treated with antifungal medications, but home remedies can… READ MORE Fungal infections, including fungal skin infections, oral candidiasis (oral thrush), and vulvovaginal candidiasis ( vaginal thrush). More recently, gentian violet has been used to treat oral thrush in patients who are HIV-positive. Sun M, et al, Office of Environmental Health Hazard Assessment’s (OEHHA) Reproductive and Cancer Hazard Assessment Branch. (2019 update). Evidence on the carcinogenicity of gentian violet.

Gentian violet | DermNet

Pappas PG, et al. (2016). Clinical practice guideline for the management of candidiasis: 2016 Update by the Infectious Diseases Society of America. Bhandarkar SS, et al. Targeted therapy of oral hairy leukoplakia with gentian violet. J Am Acad Dermatol 2008;58:711–2 The length of time it takes for mold to cause symptoms varies greatly. The side effects can be immediate, delayed, or nonexistent. READ MORETreatments for thrush other than gentian violet include the azole antifungal medications. These require a prescription. Your doctor can help you decide which treatment is best for your particular situation. If you are breastfeeding or chestfeeding, symptoms of thrush are often some scaling and redness around your nipples. Or you may notice a deep, burning pain that lasts through the feeding. It’s also important to note that gentian violet is on the Proposition 65 list, and it’s been said that exposure may increase risk of cancer. Due to the concerns noted above, you should wash your nipples before breastfeeding your baby, unless directed otherwise by a pediatrician. Adults Note: Next day delivery is unavailable to more rural regions & areas. Other delivery timescales to these areas may also be affected.

Gentian Violet, First Aid Antiseptic, 1 fl oz (30 ml) De La Cruz, Gentian Violet, First Aid Antiseptic, 1 fl oz (30 ml)

Edwards K. (2017). New twist on an old favorite: Gentian violet and methylene blue antibacterial foams. Gentian violet is also an option to treat thrush in people where Candida albicans, the fungus that causes thrush, develops resistance to antifungal medications. If you do decide to use it, be very careful to follow your doctor’s dosage and use instructions. Solution strength and dosage amounts are especially important when using gentian violet. Using too much or too strong of a solution can cause side effects. If you’ve been using gentian violet for a week and don’t see an improvement, reach out to your healthcare professional to see whether there’s another reason for the pain you feel. The use of gentian violet to treat thrush declined in the face of these new antifungal medications, which proved very effective in treating thrush.FDA (2016). FDA Executive Summary: Classification of wound dressings combined with drugs, Prepared for the Meeting of the General and Plastic Surgery Devices Advisory Panel September 20-21, 2016. People and clinicians continue to use it because it is known to be very effective against thrush, and it is inexpensive. Cost can be a critical factor in communities and health facilities around the world where finances are limited.