If a player attempts to use the crucifix in The Rooms, there will be a message saying "Your crucifix feels lighter than normal.

If Void is likely to appear and the player is not on low health and is wanting to use the crucifix later on, unequip the crucifix immediately to prevent it consumed by Void. It also contains a crescent in the middle of the hexagram, which is depicted as the Islamic crescent.This message, when translated and ran through the Caesar cipher, reads "OneOfTheThreeArchitectsMarkedByCelestialsAssistsYou. Alternatively, using it against Ambush or Halt is recommended, as they're arguably very difficult entities to survive.

This is actually because when they watch Seek being banished, the chase is still ongoing, multiple doors have been opened, and they have been teleported by Void. Using a crucifix on Rush is only useful if all closets are taken or a double-rush occurs in the Greenhouse. The crucifix cannot be used on non-harmful or docile entities such as Jack, Sally, Shadow, Glitch, Guiding Light, Curious Light, Jeff, El Goblino and Bob. Please read the Wiki Rules and the Manual of Style before contributing to get a better understanding of what content is allowed on our wiki and how to display it properly. This also applies even if the crucifix is failing to work, though the chains eventually glow red and break.Using crucifix on Ambush is effective if there are not enough closets or if a player is unexperienced. It is not recommended to use the crucifix on entities such as Dupe or Eyes as such entities are easy to avoid.

There is reason to suspect that the crucifix's design is inspired by Phasmophobia's crucifix due to the similarity in their designs. These are based on gameplay experiences and how the crucifix might be useful or not during some situations. In the sigil's inner circle is a message in the font "WingDings", a font that displays letters as symbols.

The crucifix does not work on April Fools Exclusive Entities (Jeff The Killer, Banana Peel, Greed, Evil Key, Subspace Tripmine).