Yu G, Xiang W, Zhang T, Zeng L, Yang K, Li J. Effectiveness of Boswellia and Boswellia extract for osteoarthritis patients: a systematic review and meta-analysis. BMC Complement Med Ther. 2020;20(1):225. View abstract.

El Fortia, M., Badi, H., Elalem, Kh, Kadiki, O., and Topov, Y. Olibanum bezoar: complication of a traditional popular medicine. East Mediterr.Health J 2006;12(6):927-929. View abstract. Boswellic acid may also have a role in asthma treatment. Research findings have shown that boswellic acid suppresses inflammation in the airways and inhibits the secretion of cytokines, which are markers that lead to inflammation. Reddy, G. K., Chandrakasan, G., and Dhar, S. C. Studies on the metabolism of glycosaminoglycans under the influence of new herbal anti-inflammatory agents. Biochem Pharmacol 10-15-1989;38(20):3527-3534. View abstract.Boswellia is a key ingredient in Nutraquin+ and Nutramedwhich arenaturaljoint supplements for dogs, cats and horses, which contain the necessary high quality ingredients that help to maintain healthy joint function. Benefits of Boswellia for joints: In addition, Boswellia is believed to play a role in maintaining healthy matrix metalloproteinase (MMP) activity, which supports connective tissue structural composition. MMPs, are a large group of (zinc dependant) enzymes which cleave the constituents of the extracellular matrix and are thought to play a role in joint destruction. Boswellia for dogs, cats and horses Chande, N., McDonald, J. W., and MacDonald, J. K. Interventions for treating collagenous colitis. Cochrane.Database.Syst.Rev 2006;(4):CD003575. View abstract.

Galeone, G., Spadavecchia, R., Balducci, M. T., and Pagliarulo, V. [The role of Proxelan in the treatment of chronic prostatitis. Results of a randomized trial]. Minerva Urol.Nefrol. 2012;64(2):135-141. View abstract. Gomaa AA, Mohamed HS, Abd-Ellatief RB, Gomaa MA, Hammam DS. Advancing combination treatment with glycyrrhizin and boswellic acids for hospitalized patients with moderate COVID-19 infection: a randomized clinical trial. Inflammopharmacology 2022;30(2):477-486. View abstract.Results Of 47 potentially relevant studies, seven met all inclusion criteria (five placebo controlled, two with active controls). The included trials related to asthma, rheumatoid arthritis, Crohn’s disease, osteoarthritis, and collagenous colitis. Results of all trials indicated that B serrata extracts were clinically effective. Three studies were of good methodological quality. No serious safety issues were noted. Kulkarni RR, Patki PS, Jog VP, and et al. Efficacy of an Ayurvedic formulation in rheumatoid arthritis: a double-blind, placebo-controlled, cross-over study. Indian J Pharm 1992;24:98-101. Gomaa AA, Mohamed HS, Abd-Ellatief RB, et al. Boswellic acids/ Boswellia serrata extract as a potential COVID-19 therapeutic agent in the elderly. Inflammopharmacology. 2021;29(4):1033-1048. doi:10.1007/s10787-021-00841-8 Sengupta K, Krishnaraju AV, Vishal AA, et al. Comparative efficacy and tolerability of 5-Loxin and Aflapin against osteoarthritis of the knee: a double blind, randomized, placebo controlled clinical study. Int J Med Sci 2010;7:366-77. View abstract.

Sontakke S, Thawani V, Pimpalkhute S, et al. Open, randomized, controlled clinical trial of Boswellia serrata extract as compared to valdecoxib in osteoarthritis of knee. Indian Journal of Pharmacology 2007;39:27-9. Kizhakkedath R. Clinical evaluation of a formulation containing Curcuma longa and Boswellia serrata extracts in the management of knee osteoarthritis. Mol Med Rep 2013;8(5):1542-8. View abstract. Madisch A, Miehlke S, Eichele O, et al. Boswellia serrata extract for the treatment of collagenous colitis. A double-blind, randomized, placebo-controlled, multicenter trial. Int J Colorectal Dis 2007;22:1445-51. View abstract. Boswellia serrata has been directly connected to reducing inflammation in the gut, which is the cause of many digestive problems, from Irritable Bowel Syndrome to constipation and stomach upset. By eliminating this inflammation, thanks to boswellic acid, nutrient uptake efficiency can be improved and symptoms of diarrhea, bloating and cramping can be relieved, in addition to a lower risk of gastric ulcers and other chronic conditions. [11] Hormone BalanceBaram SM, Karima S, Shateri S, et al. Functional improvement and immune-inflammatory cytokines profile of ischaemic stroke patients after treatment with boswellic acids: a randomized, double-blind, placebo-controlled, pilot trial. Inflammopharmacology 2019;27(6):1101-12. View abstract. Yu G, Xiang W, Zhang T, Zeng L, Yang K, Li J. Effectiveness of Boswellia and Boswellia extract for osteoarthritis patients: a systematic review and meta-analysis. BMC Complement Med Ther. 2020;20(1):225. doi:10.1186/s12906-020-02985-6