Pain Hub T-Shirt

Product Information

answer why people with the same visceral disease can have completely different pain experiences, including flares evidence enhanced service delivery through additional publishable case studies that demonstrate further impact and value to researchers, innovators, people with pain and populations Allowing linkage of these pain datasets to other relevant datasets, including routine health and social care records (e.g. prescribing and hospital admission), and research on other relevant conditions (e.g. mental health). This is a mandatory attachment, however, given that its anticipated content should be contained within the case for support, please upload a blank attachment. CVs and list of publications

We will look especially for people at the extremes: those with little pain despite clear disease, and those with severe pain despite few signs of disease. We will record their pain using standard self-report methods, but also explore other ways to capture their experience; for example, using automatic sensors to record activity and physiological changes throughout the day. To find out what causes severe pain in some people, we will study the genetic and immune systems of participants. When developing costings, applicants should take careful note to differentiate the hub’s activities from existing funding for related work by the members of the application.One of our Patient Insight Partners (PIP) provided the analogy: “You have to put books in the library to enhance knowledge.” The proposed use of innovative approaches to data discovery, standardisation, curation and cleaning, along with automation and a scalable secure infrastructure will create a powerful resource, that will be informed by what matters to people living with chronic pain. Our work will be divided into various taskforces, each led by an internationally recognised expert clinician or scientist. All research will be enriched by input from patient and patient support organisations from start to finish. have strong leadership, deep domain expertise and governance, including plans for including people with pain and members of the public in decision-making and governance and how the hub will ensure that research outcomes from its work are linked to patient benefits the physical environment the partnership will provide as a hub base to support collaboration and innovations across a range of users (for example data scientists, clinicians) from industry, the NHS and academia The consortia will bring together leadership, infrastructure, capability, tools and resources to lay the foundation of an enduring programme that will underpin a broader portfolio of pain research supported by UKRI, Versus Arthritis and others.

Making available high quality, chronic pain focused research datasets to researchers, safely and securely within the HIC Trusted Research Environment. https://www.tiktok.com/embed/v2/6934131738658622726 https://www.tiktok.com/embed/v2/6934174853549296902 Consortium Against Pain InEquality (CAPE) – The impact of adverse childhood experiences on chronic pain and responses to treatment harness opportunities to work across the HDR UK Hub network and link to or complement relevant existing investments, nationally and internationally

World class infrastructure

Maximum one side of A4, including a project plan and risk register with mitigating actions. Data management plan

evidence of plans to work in close partnership with the APDP consortia and other APDP investments to bring their data into the hub for curation, linkage and wider community access, including plans for consistent policies and governance frameworks for data access and sharing to maximise interoperability across the APDP investments You can also include international co-investigators if they provide expertise that is not available in the UK. We expect a demonstrable commitment to patient involvement in the development and implementation of the data hub. synergising research across existing data hubs whilst bringing in innovative research from other domains which will significantly enhance scientific knowledge potential for economic and societal impact that would otherwise not be possible without the establishment of a research data hub.

Major unmet health challenge

Consortium Against Pain in Equality (CAPE), led by Professor Tim Hales, University of Dundee, researching the impact of adverse childhood experiences on chronic pain and responses to treatment Milestone three: impact, sustainability and scalability (within two and a half years of becoming a hub)