B Braun D5613 Wound Irrigation Solution, 350ml

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Riesgo AM, Park BK, Herrero CP, Yu S, Schwarzkopf R, Iorio R. Vancomycin Povidone-Iodine Protocol Improves Survivorship of Periprosthetic Joint Infection Treated With Irrigation and Debridement. J Arthroplasty. 2018; 33:847–850. [ PubMed] [ Google Scholar] Andriessen AE, Eberlein T. Assessment of a wound cleansing solution in the treatment of problem wounds. Wounds 2008; 20(6):171–175 In Vitro Evaluation of Polihexanide, Octenidine and NaClO/HClO-BasedAntiseptics against Biofilm Formed by Wound Pathogens

Analysis of Anti-Biofilm Effect of Intraoperative Irrigation Solutions. AAHKS; 2020. [ Google Scholar] Clinician perspective on time and resource related to dressing changes. Available at https://www.wounds-uk.com/journals/issue/506/article-details/clinician-perspectives-on-time-and-resources-related-to-dressing-changes [accessed Jan 2021]Goswami K, Austin MS. Intraoperative povidone-iodine irrigation for infection prevention. Arthroplasty Today. 2019; 5:306–308. a. [ PMC free article] [ PubMed] [ Google Scholar] Debriding aids in the removal of biofilm, debris and slough from the wound bed. Combined with the use of a surfactant based wound cleansing solution, it will cleanse the wound sufficiently to remove and disrupt the biofilm.

TKA: 96.8% (487/503) at 3 months 93.4% (298/319) at 12 months THA: 96.3% (367/381) at 3 months 94.8% (219/231) at 12 months Lineaweaver W, Howard R, Soucy D, McMorris S, Freeman J, Crain C, Robertson J, Rumley T. Topical Antimicrobial Toxicity. Arch Surg. 1985; 120:267–270. [ PubMed] [ Google Scholar] Surgical debridement → modular component explantation → 3L PI b irrigation → PI b scrub brush mechanical scrub → 3L SH b irrigation → 3L Bacitracin b irrigation → 3L NS irrigation → re-drape → component implantation Campbell ST, Goodnough LH, Bennett CG, Giori NJ. Antiseptics Commonly Used in Total Joint Arthroplasty Interact and May Form Toxic Products. J Arthroplasty. 2018; 33:844–846. [ PubMed] [ Google Scholar]International Wound Infection Institute. Wound infection in clinical practice. Wounds International, 2016 George DA, Konan S, Haddad FS. Single-Stage Hip and Knee Exchange for Periprosthetic Joint Infection. J Arthroplastym. 2015; 30:2264–2270. [ PubMed] [ Google Scholar] Andriessen AE, Eberlein T. Assessment of a wound cleansing solution in the treatment of problem wounds. Wounds: A Compendium of Clinical Research & Practice 2008; 20(6): 171-5. Created by white blood cells during the oxidative burst to kill pathogens. HOCl is additionally produced by neutrophils, macrophages, monocytes, andmyeloperoxidase-catalyzed peroxidation ofchloride ions. The residual chloride ions oxidize the surrounding bacterial cells in a similar mechanism to sodium hypochlorite, except in a slightly more acidic pH5.5. Total Knee Arthroplasty Revision Surgery in Known Cases of Prosthetic Joint Infection. [last access: 10May2021]; 2019 available at: https://www.zimmerbiomet.com/content/dam/zimmer-biomet/medical-professionals/surgical-and-cement/bactisure-wound-lavage/2656.1%20US-en%20Bactisure%20White%20Paper.pdf . [ Google Scholar]

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Rabenberg VS, Ingersoll CD, Sandrey MA, Johnson MT. The bactericidal and cytotoxic effects of antimicrobial wound cleansers. J Athl Training. 2002; 37:51–54. [ PMC free article] [ PubMed] [ Google Scholar] Cichos KH, Andrews RM, Wolschendorf F, Narmore W, Mabry SE, Ghanem ES. Efficacy of Intraoperative Antiseptic Techniques in the Prevention of Periprosthetic Joint Infection: Surgical debridement → explantation → PI b , c and H 2O 2 b , c irrigations → PI b , c soak → re-drape →“lavage” → component implantation development by Staphylococcus epidermidis compared to an untreated control group. Zubko and Zubko (2013) reported the Marx RG, Wilson SM, Swiontkowski MF. Updating the Assignment of Levels of Evidence. Journal Bone Joint Surg. 2015; 97:1–2. doi: 10.2106/JBJS.N.01112. [ PubMed] [ CrossRef] [ Google Scholar]

Solution for acute, chronic and burn wounds

Ruder JA, Springer BD. Treatment of Periprosthetic Joint Infection Using Antimicrobials: Dilute Povidone–Iodine Lavage. J Bone Joint Infect. 2017; 2:10–14. doi: 10.7150/jbji.16448. [ PMC free article] [ PubMed] [ CrossRef] [ Google Scholar]