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When you're ready to use them, you simply crush them with a mortar and pestle. Or grind them in a pepper mill. This way, you're getting the freshest flavor possible. Though no human trials have been performed, test-tube studies found that piperine slowed the replication of breast, prostate, and colon cancer cells and induced cancer cell death ( 37, 38, 39, 40). Jirovetz, L; Buchbauer, G; Ngassoum, M. B.; Geissler, M (2002). "Aroma compound analysis of Piper nigrum and Piper guineense essential oils from Cameroon using solid-phase microextraction-gas chromatography, solid-phase microextraction-gas chromatography-mass spectrometry and olfactometry". Journal of Chromatography A. 976 (1–2): 265–75. doi: 10.1016/s0021-9673(02)00376-x. PMID 12462618.
Stephanie Fitzgerald (8 September 2008). Ramses II, Egyptian Pharaoh, Warrior, and Builder. Compass Point Books. p.88. ISBN 978-0-7565-3836-1 . Retrieved 29 January 2008.However, excessive free radicals can be formed with exposure to things like pollution, cigarette smoke, and sun rays ( 3). Aggarwal, Bharat B.; Kunnumakkara, Ajaikumar B. (2009). Molecular Targets and Therapeutic Uses of Spices: Modern Uses for Ancient Medicine. World Scientific. pp.26–27. ISBN 978-981-283-791-2 . Retrieved 28 March 2022.
When you grind them yourself, you can adjust the coarseness of the grind. It can affect the intensity of the flavor. Plus, if you're using a pepper mill, you can adjust the size of the grind as you go, giving you even more control.Definitely not! Each type has its own unique flavor profile and best uses. It's like comparing a cowboy to a fine gentleman. Both have their strengths, but they're definitely not the same!