Vape Blue Elf Bar Disposable Vape, 600 Puffs, Zero Nicotine, Pack of 4, Blueberry, Cherry, Watermelon, Grape

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Smoking and Tobacco Control Monograph No. 9" (PDF). Archived (PDF) from the original on 9 October 2022 . Retrieved 19 December 2012.

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adults and children over 12 years of age – although children under 18 should not use the lozenges without getting medical advice first a b c d e f g h Siegmund B, Leitner E, Pfannhauser W (August 1999). "Determination of the nicotine content of various edible nightshades (Solanaceae) and their products and estimation of the associated dietary nicotine intake". Journal of Agricultural and Food Chemistry. 47 (8): 3113–20. doi: 10.1021/jf990089w. PMID 10552617. Caponnetto P, Campagna D, Papale G, Russo C, Polosa R (February 2012). "The emerging phenomenon of electronic cigarettes". Expert Review of Respiratory Medicine. 6 (1): 63–74. doi: 10.1586/ers.11.92. PMID 22283580. S2CID 207223131.The answer to the question ‘Are Elf Bars bad for you?’ is best answered with another question: why are you using Elf Bars? If you’re using them as a stop-smoking aid, then they’re far better for your health than cigarettes. With that said, no e-cigarette is 100% safe (a massive study by Public Health England found vaping to be at least 95% safer ) so unless you’re a smoker then we’d strongly advise against using any vaping devices including the Elf Bar. How much nicotine is in a Elf Bar? a b c d "Nicotinic acetylcholine receptors: Introduction". IUPHAR Database. International Union of Basic and Clinical Pharmacology. Archived from the original on 29 June 2017 . Retrieved 1 September 2014. Nicotine is a secondary metabolite produced in a variety of plants in the family Solanaceae, most notably in tobacco Nicotiana tabacum, where it can be found at high concentrations of 0.5 to 7.5%. [172] Nicotine is also found in the leaves of other tobacco species, such as Nicotiana rustica (in amounts of 2–14%). Nicotine production is strongly induced in response to wounding as part of a jasmonate-dependent reaction. [173] Specialist insects on tobacco, such as the tobacco hornworm ( Manduca sexta), have a number of adaptations to the detoxification and even adaptive re-purposing of nicotine. [174] Nicotine is also found at low concentrations in the nectar of tobacco plants, where it may promote outcrossing by affecting the behavior of hummingbird pollinators. [175]

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A racing heartbeat may mean the dose of nicotine is too high, and people can talk with a healthcare professional about lowering the dosage. Nicotine acts as a receptor agonist at most nicotinic acetylcholine receptors (nAChRs), [11] [12] except at two nicotinic receptor subunits ( nAChRα9 and nAChRα10) where it acts as a receptor antagonist. [11] Such antagonism results in mild analgesia. Nicotine-containing products are sometimes used for the performance-enhancing effects of nicotine on cognition. [57] A 2010 meta-analysis of 41 double-blind, placebo-controlled studies concluded that nicotine or smoking had significant positive effects on aspects of fine motor abilities, alerting and orienting attention, and episodic and working memory. [58] A 2015 review noted that stimulation of the α4β2 nicotinic receptor is responsible for certain improvements in attentional performance; [59] among the nicotinic receptor subtypes, nicotine has the highest binding affinity at the α4β2 receptor (k i=1 nM), which is also the biological target that mediates nicotine's addictive properties. [60] Nicotine has potential beneficial effects, but it also has paradoxical effects, which may be due to the inverted U-shape of the dose-response curve or pharmacokinetic features. [61] Recreational [ edit ]Tharp C (5 September 2014). "Safety for Homemade Remedies for Pest Control" (PDF). Montana Pesticide Bulletin. Montana State University. Archived from the original (PDF) on 5 September 2014 . Retrieved 21 September 2020. In the United States, nicotine products and Nicotine Replacement Therapy products like Nicotrol are only available to persons 18 and above; proof of age is required; not for sale in vending machine or from any source where proof of age cannot be verified. As of 2019, the minimum age to use tobacco in the US is 21 at the federal level. [191] Royal College of Physicians. "Nicotine Without Smoke -- Tobacco Harm Reduction". p.125 . Retrieved 30 September 2020. Use of nicotine alone, in the doses used by smokers, represents little if any hazard to the user. Boutrel B, Koob GF (September 2004). "What keeps us awake: the neuropharmacology of stimulants and wakefulness-promoting medications". Sleep. 27 (6): 1181–94. doi: 10.1093/sleep/27.6.1181. PMID 15532213. An e-cigarette is an electronic device that delivers nicotine in a vapour. This allows you to inhale nicotine without most of the harmful effects of smoking, as the vapour contains no tar or carbon monoxide.

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Nicotine was often compared to caffeine in advertisements in the 1980s by the tobacco industry, and later in the 2010s by the electronic cigarettes industry, in an effort to reduce the stigmatization and the public perception of the risks associated with nicotine use. [194] Research [ edit ] Central nervous system [ edit ] Tobacco was introduced to Europe in 1559, and by the late 17th century, it was used not only for smoking but also as an insecticide. After World War II, over 2,500 tons of nicotine insecticide were used worldwide, but by the 1980s the use of nicotine insecticide had declined below 200 tons. This was due to the availability of other insecticides that are cheaper and less harmful to mammals. [17] Varenicline (brand name Champix) is not currently available. It has been withdrawn as a precaution because of an impurity found in the medicine. It's not yet known whether it will be available again in future.

a b c d e f g Parrott AC (April 2003). "Cigarette-derived nicotine is not a medicine". The World Journal of Biological Psychiatry. 4 (2): 49–55. doi: 10.3109/15622970309167951. PMID 12692774. S2CID 26903942. Randomized trials and observational studies of nicotine replacement therapy in cardiovascular patients show no increase in adverse cardiovascular events compared to those treated with placebo. [73] Using nicotine products during cancer treatment may be contraindicated, as nicotine may promote tumour growth, but temporary use of NRTs to quit smoking may be advised for harm reduction. [74] Nicotine may also temporarily improve concentration and memory. However, long-term smoking of cigarettes may link to a decline in cognitive ability and an increased risk of Alzheimer’s disease. Therefore, any short-term benefits on cognitive function do not outweigh the long-term risks from nicotine use.

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https://www.fda.gov/tobacco-products/health-effects-tobacco-use/nicotine-why-tobacco-products-are-addictive Nicotine has been used as an insecticide since at least the 1960s, in the form of tobacco extracts [17] [48] [49] (although other components of tobacco also seem to have pesticide effects). [50] Nicotine pesticides have not been commercially available in the US since 2014, [51] and homemade pesticides are banned on organic crops [52] and caution is recommended for small gardeners. [53] Nicotine pesticides have been banned in the EU since 2009. [54] Foods are imported from countries in which nicotine pesticides are allowed, such as China, but foods may not exceed maximum nicotine levels. [54] [55] Neonicotinoids, such as imidacloprid, which are derived from and structurally similar to nicotine, are widely used as agricultural and veterinary pesticides as of 2016. [56] [48] Performance [ edit ] E-cigarettes containing nicotine are not suitable for pregnant people, as nicotine may cause prenatal development issues. a b Nicotine. 16 February 2019 . Retrieved 31 October 2023. {{ cite encyclopedia}}: |work= ignored ( help)Smoking is the most common preventable cause of death in the United States. Smoking causes damage to almost every organ in the body and increases the risk of severe health problems, including heart disease, stroke, and lung cancer. The tobacco industry has a substantial history of using racial profiling, demographics of an area, and cultural factors to target particular communities and promote tobacco use. Nausea, dyspepsia, flatulence, headache, upper respiratory tract infections, irritation (i.e., a burning sensation), hiccups, sore throat, coughing, dry lips, and oral mucosal ulceration. Although nicotine itself does not cause cancer in humans, [38] it is unclear whether it functions as a tumor promoter as of 2012 [update]. [102] A 2018 report by the US National Academies of Sciences, Engineering, and Medicine concludes, "[w]hile it is biologically plausible that nicotine can act as a tumor promoter, the existing body of evidence indicates this is unlikely to translate into increased risk of human cancer." [103] Now we know how much nicotine they contain, you might also be wondering how many cigarettes in an Elf Bar. The short answer is none as cigarettes contain over 5,000 chemicals including tar and carbon monoxide, neither of which are found in Elf Bars.