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The systemic concentration of diclofenac is lower after topical administration, compared to oral formulations.
Motusol Max should only be used under medical advice during breast-feeding as diclofenac passes into breast milk in small amounts.Undesirable effects similar to those observed following an overdose of systemic diclofenac can occur if topical diclofenac is inadvertently ingested (1 tube of 100 g contains the equivalent of 2,320 diclofenac diethylamine corresponding to 2,000 mg diclofenac sodium). In addition, the gel significantly improved functioning of the foot joint within the first three days of treatment.
g. renal, hepatic or gastrointestinal undesirable effects, systemic hypersensitivity reactions) - as they occur possibly after systemic administration of diclofenac-containing medicinal products cannot be excluded. The other ingredients are isopropyl alcohol, propylene glycol (E1520), cocoyl caprylocaprate, liquid paraffin, carbomer, macrogol cetostearyl ether, diethylamine, oleic acid (E570), butylhydroxytoluene (E321), fragrance (containing citronellol, geraniol, benzyl alcohol (E1519), linalool, limonene, citral, farnesol, coumarin, eugenol), purified water. Data from epidemiological studies suggest an increased risk of miscarriage and of cardiac malformation and gastroschisis after use of a prostaglandin synthesis inhibitor in early pregnancy.
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year toxicity study, a dose-dependent increase in the incidence of thrombosis of the heart was observed in diclofenac-treated rats. TENA Discreet Extra Plus are soft, comfortable towels which offer fast, efficient absorbency and give you the ultimate feeling of protection, so you feel instantly dry and comfortable leaving you feeling confident and fresh all day. There are insufficient data on efficacy and safety in children and adolescents under 14 years of age (see section 4.mg/g, E1519), citral, citronellol, coumarin, eugenol, farnesol, geraniol, d-limonene and linalool which may cause allergic reactions.