BiOptimizers Magnesium Breakthrough Supplement 4.0 - Has 7 Forms of Magnesium: Glycinate, Malate, Citrate, and More - Natural Sleep and Brain Supplement - 60 Capsules

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Pouteau E, Kabir-Ahmadi M, Noah L, et al. Superiority of magnesium and vitamin B6 over magnesium alone on severe stress in healthy adults with low magnesemia: A randomized, single-blind clinical trial. PLoS One. 2018;13(12):e0208454. Published 2018 Dec 18. doi:10.1371/journal.pone.0208454 DiNicolantonio JJ, Liu J, O’Keefe JH. Magnesium for the prevention and treatment of cardiovascular disease. Open Heart. 2018;5(2):e000775. Published 2018 Jul 1. doi:10.1136/openhrt-2018-000775

Chelated magnesium is a type of magnesium that is chemically bonded to an organic compound or an amino acid, examples of which include magnesium citrate and magnesium glycinate. On the other hand, non-chelated magnesium comprises magnesium oxide and magnesium sulfate. In general, chelated minerals exhibit increased bioavailability and are more efficiently absorbed through the small intestine into the bloodstream. Animals were divided into groups receiving either a standard or high-protein diet with equivalent magnesium content. The high-protein diet yielded higher apparent magnesium levels, calculated as magnesium intake minus magnesium excreted in faeces. However, this outcome was probably due to lower faecal excretion of magnesium.Magnesium and vitamin D have an important relationship in your body. Magnesium helps activate vitamin D, keeping your bones strong and healthy. Once activated, vitamin D helps control your calcium and phosphate levels.

Magnesium plays a crucial role in preventing insulin resistance, and many people with metabolic syndrome are deficient. Reddy P, Edwards LR. Magnesium Supplementation in Vitamin D Deficiency. Am J Ther. 2019;26(1):e124-e132. doi:10.1097/MJT.0000000000000538 While also helpful for the heart, magnesium orotate is believed to be the best form for metabolic improvements.A large-scale systematic and dose-response analysis found that magnesium supplementation correlated with reduced body weight and waist circumference among specific groups of people. Participants seemed to weigh less and had smaller waist circumference if they took magnesium supplements. Magnesium supplements can reduce CRP and other markers of inflammation in older adults, overweight people and those with prediabetes. Helps With Mood, Cognitive Function, and Mental Health. A magnesium supplement significantly improved[6] mood[7] after 2 weeks. Another trial found that magnesium supplements improved[8] mood in seniors with type 2 diabetes. To enhance hormone balance through magnesium supplementation, selecting the appropriate forms of magnesium is crucial for increasing intracellular magnesium levels. It is within the intracellular environment that magnesium carries out the majority of its essential work, facilitating various biochemical reactions that contribute to hormonal equilibrium. Magnesium plays a crucial role in the production of your steroid hormones (oestrogen, progesterone and testosterone) and adrenal gland hormones (cortisol and aldosterone). It does this through its role in cholesterol metabolism, enzymatic reactions and hormone receptor functions.